Response of muscle biomarkers to a football match

  • Jader Andrade Bezerra Universidade Federal do Acre
  • Romeu Paulo Martins Silva Universidade Federal do Acre - UFAC
  • João Gomes Jácome Universidade Federal do Acre - UFAC
  • Jeane Maria Moura Costa Universidade Federal do Acre - UFAC
  • Sandro Victor Alves Melo Universidade Federal do Acre - UFAC
  • José Augusto Rodrigues dos Santos Faculdade de Desporto da Universidade do Porto - PT
Keywords: CK, LDH, GGT, Muscle damage, Football

Abstract

Exhausting physical exercise damages muscular tissue. Among other factors, damage depends on training load and intensity. The aim of this study was to determine changes in enzymatic biomarkers in response to a footballmatch. The studysample was composed of 30 footballplayers aged between 18–35 years and male,divided into experimental (GE; N = 15) and control (GC; N =15) groups. Blood samples from GE and GC individuals were withdrawn before and 24 hours after the match. The following enzymes were examined: total creatine kinase (CKt), cardiac muscle creatine kinase (CKMB), lactate dehydrogenase (LDH), and gamma-glutamyl transpeptidase (GGT). In GE individuals, there were significant changes (p<0.05) in CKt (334±203 and 860±553 U/L), CKMB (30±7 and 42±11 U/L), and LDH (417±86 and 547±84 U/L) between before and after the match, respectively; GGT remained unchanged. In GCindividuals, levels were similar at the two time points.A footballgame is sufficiently aggressive to induce tissue damage, as evidenced by increased plasma levels of various enzymes. Enzyme clearance assessment might be a valuable tool for development of training programs

Author Biographies

Jader Andrade Bezerra, Universidade Federal do Acre

Professor da Universidade Federal do Acre, Graduado Em Educação Fí­sica, pela Universidade Federal do Acre, Mestre em Ciência da Motricidade Humana pela Universidade Castelo Branco, Doutorando em Ciências do Desporto pela Faculdade de Desporto da Universidade do Porto - PT

Romeu Paulo Martins Silva, Universidade Federal do Acre - UFAC

Professor da Universidade Federal do Acre. Doutor em Genética e Bioquí­mica pela Universidade Federal de Uberlândia, Brasil(2011)

João Gomes Jácome, Universidade Federal do Acre - UFAC

Graduado em Educação Fí­sica. Profesor da Universidade Federal do Acre.

Jeane Maria Moura Costa, Universidade Federal do Acre - UFAC

Graduada em Educação Fí­sica. Professora da Universidade Federal do Acre.

Sandro Victor Alves Melo, Universidade Federal do Acre - UFAC

Graduado em Educação Fí­sica. Professor da Universidade Federal do Acre.

José Augusto Rodrigues dos Santos, Faculdade de Desporto da Universidade do Porto - PT

Professor Associado com Agregação da FADEUP. Doutor em Biologia do Desporto pela Faculdade de Desporto da Universidade do Porto (1995).

References

-Alpert, J. S.; Thygesen, K.; Antman, E.; Bassand, J. P. Myocardial infarction redefined--a consensus document of The Joint European Society of Cardiology/American College of Cardiology Committee for the redefinition of myocardial infarction. J Am Coll Cardiol. Vol. 36. Núm. 3. 2000. p. 959-969.

-Andrzejewski, M.; Domaszewska, K.; Chmura, J.; Rychlewski, T.; Kubalewska, M. Influence of speed training loads on the activity of creatine kinase and lactic dehydrogenase and the concentration of oxypurines in blood samples of young football players. Medycyna Sportowa. Vol. 24. Núm. 3. 2008. p. 149-158.

-Angelini, C. Limb-girdle muscular dystrophies: heterogeneity of clinical phenotypes and pathogenetic mechanisms. Acta Myologica: Myopathies And Cardiomyopathies: Official Journal Of The Mediterranean Society Of Myology / Edited By The Gaetano Conte Academy For The Study Of Striated Muscle Diseases. Vol. 23. Núm. 3. 2004. p. 130-136.

-Armstrong, L. E.; VanHeest, J. L. The unknown mechanism of the overtraining syndrome: clues from depression and psychoneuroimmunology. Sports Medicine. Vol. 32. Núm. 3. 2002. p. 185-209.

-Brancaccio, P.; Lippi, G.; Maffulli, N. Biochemical markers of muscular damage. Clin Chem Lab Med. Vol. 48. Núm. 6. 2010. p. 757-767.

-Clarkson, P. M.; Hubal, M. J. Exercise-induced muscle damage in humans. Am J Phys Med Rehabil. Vol. 81. Suppl 11. 2002. p. 52-69.

-Ehlers, G. G.; Ball, T. E.; Liston, L. Creatine Kinase Levels are Elevated During 2-A-Day Practices in Collegiate Football Players. Journal of Athletic Training. Vol. 37. Núm. 2. 2002. p. 151-156.

-Ekblom, B. Applied physiology of soccer. Sports Medicine. Vol. 3. 1986. p. 50-60.

-Fallon, K. E.; Sivyer, G.; Sivyer, K.; Dare, A. The biochemistryof runners in a 1600 km ultramarathon. Br J Sports Med. Vol. 33. Núm. 4. 1999. p. 264-269.

-Gojanovic, B.; Feihl, F.; Gremion, G.;Waeber, B. Muscle enzyme activity and exercise. Praxis. Vol. 98. Núm. 3. 2009. p. 133-139.

-Ispirlidis, I.; Fatouros, I. G.; Jamurtas, A. Z.; Nikolaidis, M. G.; Michailidis, I.; Douroudos, I. Time-course of changes in inflammatory and performance responses following a soccer game. Clin J Sport Med. Vol. 18. Núm. 5. 2008. p. 423-431.

-Jastrzębski, Z.; Przybylski, W.A Character of the Typical Training Microcycle in Footballers during a Competition Period. Research Yearbook. Vol. 14. Núm. 2. 2008. p. 78-84.

-Kendall, B.; Eston, R. Exercise-induced muscle damage and the potential protective role of estrogen. / Les lesions musculaires provoquees par l ' exercice et le role potentiel de protection des oestrogenes. Sports Medicine. Vol. 32. Núm. 2. 2002. p. 103-123.

-Kraemer, W. J.; Spiering, B. A.; Volek, J. S.; Martin, G. J.; Howard, R. L.; Ratamess, N. A. Recovery from a national collegiate athletic association division I football game: muscle damage and hormonal status. J Strength Cond Res. Vol. 23. Núm. 1. 2009. p. 2-10.

-Kratz, A.; Lewandrowski, K. B.; Siegel, A. J.; Chun, K. Y.; Flood, J. G.; Van Cott, E.M. Effect of marathon running on hematologic and biochemical laboratory parameters, including cardiac markers. Am J Clin Pathol. Vol. 118. Núm. 6. 2002. p. 856-863.

-Lazarim, F. L.; Antunes-Neto, J. M.; Silva, F. O.; Nunes, L. A.; Bassini-Cameron, A.;Cameron, L. C. The upper values of plasma creatine kinase of professional soccer players during the Brazilian National Championship. Journalof Science & Medicine in Sport. Vol. 12. Núm. 1. 2009. p. 85-90.

-Lippi, G.; Schena, F.; Montagnana, M.; Salvagno, G. L.; Banfi, G.;Guidi, G. C. Significant variation of traditional markers of liver injury after a half-marathon run. Eur J Intern Med. 2011. p. 3-6.

-Lippi, G.; Schena, F.; Salvagno, G. L.; Montagnana, M.; Gelati, M.; Tarperi, C. Acute variation of biochemical markers of muscle damage following a 21-km, half-marathon run. Scandinavian Journal of Clinical and Laboratory Investigation. Vol. 68. Núm. 7. 2008. p. 667-672.

-Lowbeer, C.; Seeberger, A.; Gustafsson, S. A.; Bouvier, F.;Hulting, J. Serum cardiac troponin T, troponin I, plasma BNP and left ventricular mass index in professional football players. J Sci Med Sport. Vol. 10. Núm. 5. 2007. p. 291-296.

-McLellan, C. P.; Lovell, D. I.; Gass, G. C. Creatine kinase and endocrine responses of elite players pre, during, and post rugby league match play. J Strength Cond Res. Vol. 24. Núm. 11. 2010. p. 2908-2919.

-Mougios, V. Reference intervals for serum creatine kinase in athletes. Br J Sports Med. Vol. 41. Núm. 10. 2007. p. 674-678.

-Mujika, I.; Padilla, S. Muscular characteristics of detraining in humans. Med Sci Sports Exerc. Vol. 33. Núm. 8. 2001. p. 1297-1303.

-Paschalis, V.; Koutedakis, Y.; Jamurtas, A. Z.; Mougios, V.; Baltzopoulos, V. Equal volumes of high and low intensityof eccentric exercise in relation to muscle damage and performance. J Strength Cond Res. Vol. 19. Núm. 1. 2005. p. 184-188.

-Pettersson, J.; Hindorf, U.; Persson, P.;Bengtsson, T.; Malmqvist, U.;Werkstrom, V. Muscular exercise can cause highly pathological liver function tests in healthy men. Br J Clin Pharmacol. Vol. 65. Núm. 2. 2008. p. 253-259.

-Rodrigues dos Santos, J. A. Alterações agudas induzidas por uma corrida de 50-Km em alguns parãmetros hematológicos, bioquímicos e urinários em sujeitos com diferentes níveis de treino. Rev Port Med Desp. Vol. 22. 2004. p. 11-22.

-Roth, H. J.; Leithauser, R. M.; Doppelmayr, H.; Doppelmayr, M.; Finkernagel, H.; von Duvillard, S. P. Cardiospecificity of the 3rd generation cardiac troponin T assay during and after a 216 km ultra-endurance marathon run inDeath Valley. Clin Res Cardiol. Vol. 96. Núm. 6. 2007. p. 359-364.

-Schulte-Frohlinde, E. [Isolated enhancementof gamma-GT]. Internist (Berl). Vol. 49. Núm. 12. 2008. p. 1526.

-Schumann, G.; Klauke, R. New IFCC reference procedures for the determination of catalytic activity concentrations of five enzymes in serum: preliminary upper reference limits obtained in hospitalized subjects. Clin Chim Acta. Vol. 327. Núm. 1-2. 2003. p. 69-79.

-Senel, Ö.; Akyüz, M. The occurrence of muscle damage in male soccer players. Ovidius University Annals, Series Physical Education & Sport/Science, Movement & Health. Vol. 10. Núm. 1. 2010. p. 55-59.

-Skenderi, K. P.; Kavouras, S. A.; Anastasiou, C. A.; Yiannakouris, N.; Matalas, A. L. Exertional Rhabdomyolysis during a 246-km continuous running race. Med Sci Sports Exerc. Vol. 38. Núm. 6. 2006. p. 1054-1057.

-Smith, J. E.; Garbutt, G.; Lopes, P.; Pedoe, D. T. Effects of prolonged strenuous exercise (marathon running) on biochemical and haematological markers used in the investigation of patients in the emergency department. Br J Sports Med. Vol. 38. Núm. 3. 2004. p. 292-294.

-Soeder, G.; Golf, S. W.; Graef, V.; Temme, H.; Brustle, A.;Roka, L. Enzyme catalytic concentrations in human plasmaafter a marathon. Clin Biochem. Vol. 22. Núm. 2. 1989. p. 155-159.

-Totsuka, M.; Nakaji, S.; Suzuki, K., Sugawara, K.;Sato, K. Break point of serum creatine kinase release after endurance exercise. [Article]. J Appl Physiol. Vol. 93. 2002. p. 1280-1286.

-Ziegler, S.; Niessner, A.; Slany, J.; Müller, M. M.; Heinschink, A.;Billensteiner, E. Muscle cell proteins are selectively released into the blood stream by marathon running. Acta Medica Austriaca. Vol. 30. Núm. 2. 2003. p. 55-58.

Published
2013-12-27
How to Cite
Bezerra, J. A., Silva, R. P. M., Jácome, J. G., Costa, J. M. M., Melo, S. V. A., & Santos, J. A. R. dos. (2013). Response of muscle biomarkers to a football match. RBFF - Brazilian Journal of Futsal and Football, 6(19). Retrieved from https://www.rbff.com.br/index.php/rbff/article/view/251
Section
Scientific Articles - Original